For people who had two initial doses of the Oxford/AstraZeneca vaccine, the UKHSA estimates that Pfizer/BioNTech or Moderna boosters are around 60 per cent effective at preventing symptomatic infections from omicron 2 to 4 weeks after the third dose, but this falls to 35 to 45 per cent by 10 weeks. ![]() Based on an analysis of 147,597 delta and 68,489 omicron cases, the agency found that the Oxford/AstraZeneca, Pfizer/BioNTech and Moderna vaccines are less effective against omicron than delta.
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